vault and manual backup jobs cannot be kicked off

We have an issue to view "activity monitor" this morning. After restarted NBU, looks all scheduled jobs can be kicked off and work well. But we still cannot manually kick off any backup and vault jobs. Does anyone encounter same issue and have a solution? We have a NBU ticket open already but still wait for the reply.

NBU 7.1.0.4 on HP-UX 11.31.

thanks in advance.